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A potential new tool for the toolbox: assessing gene drives for eradicating invasive rodent populations
Biodiversity Conservation, BRB
Available Online

Brown, P.R.

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Campbell, K.J.

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Delborne, J.

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Godwin, J.

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Gould, F.

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Howald, G.R.

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Kanavy, D.M.

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Kuiken, T.

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Packard, H.

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Piaggio, A.

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Saah, J.R.

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Serr, M.

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Shiels, A.

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Thomas, P.

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Threadgill, D.

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Tompkins, D.M.

2019
Invasive rodents have significant negative impacts on island biodiversity. All but the smallest of rodent eradications currently rely on island-wide rodenticide applications. Although significant advances have been made in mitigating unintended impacts, rodent eradication on inhabited islands remains extremely challenging. Current tools restrict eradication efforts to fewer than 15% of islands with critically endangered or endangered species threatened by invasive rodents. The Genetic Biocontrol of Invasive Rodents partnership is an interdisciplinary collaboration to develop and evaluate gene drive technology for eradicating invasive rodent populations on islands. Technological approaches currently being investigated include the production of multiple strains of Mus musculus with a modified form of the native t-complex, or a CRISPR gene drive, carrying genes or mechanisms that determine sex. These systems have the potential to skew the sex ratio of off spring to approach 100% single-sex, which could result in population collapse. One goal proposed is to test the ability of constructs to spread and increase in frequency in M. musculus populations in biosecure, captive settings and undertake modelling to inform development and potential deployment of these systems. Structured ecologically-based risk assessments are proposed, along with social and cultural engagement to assess the acceptability of releasing a gene drive system. Work will be guided by an external ethics advisory board. Partners are from three countries with significant regulatory capacity (USA, Australia, New Zealand). Thus, we will seek data sharing agreements so that results from experiments may be used within all three countries and treat regulatory requirements as a minimum. Species-specific, scalable, and socially acceptable new eradication tools could produce substantial biodiversity benefits not possible with current technologies. Gene drive innovation may provide such a tool for invasive species management and be potentially transformative and worthy of exploring in an inclusive, responsible, and ethical manner.
Integrated Climate Change Risks in the Agriculture and Health Sectors in Samoa (ICCRAHSS) - Agriculture Component: Geographical Information Systems Activities

GEF

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Ministry of Agriculture and Fisheries (Government of Samoa)

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UNDP

2010
In 1989, the Asian Development Bank provided technical assistance to the then Department of Agriculture and the Survey Department through a NZ Consulting Firm - ANZDEC under an ADB Land Resource Planning Survey Project. The Project provided training on mapping and GIS capability for the survey staff who were involved in the mapping work. Electronic GIS data and equipment were handed over to the Department of Agriculture at the end of the project which were later on damaged by Cyclone Ofa in 1990. A decade later, the Integrated Climate Change Risks in Agriculture and Health Sectors (ICCRAHSS) Project funded by the GEF through UNDP contracted the services of a consultant to provide: -improved GIS maps for soil, crops and rainfall distribution under different climatic projections; -review existing GIS systems and possible areas for collaboration; -consider a program to support capacity building on the use of the system and; -some applications that addresses options for climate change adaptation for the agriculture sector. Based on this report, a GIS system for the Ministry of Agriculture was procured to address the need for such a system to be in place with the expectation that the system will be properly utilized and maintained by relevant people.