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Invasive rodents have significant negative impacts on island biodiversity. All but the smallest of rodent eradications currently rely on island-wide rodenticide applications. Although significant advances have been made in mitigating unintended impacts, rodent eradication on inhabited islands remains extremely challenging. Current tools restrict eradication efforts to fewer than 15% of islands with critically endangered or endangered species threatened by invasive rodents. The Genetic Biocontrol of Invasive Rodents partnership is an interdisciplinary collaboration to develop and evaluate gene drive technology for eradicating invasive rodent populations on islands. Technological approaches currently being investigated include the production of multiple strains of Mus musculus with a modified form of the native t-complex, or a CRISPR gene drive, carrying genes or mechanisms that determine sex. These systems have the potential to skew the sex ratio of off spring to approach 100% single-sex, which could result in population collapse. One goal proposed is to test the ability of constructs to spread and increase in frequency in M. musculus populations in biosecure, captive settings and undertake modelling to inform development and potential deployment of these systems. Structured ecologically-based risk assessments are proposed, along with social and cultural engagement to assess the acceptability of releasing a gene drive system. Work will be guided by an external ethics advisory board. Partners are from three countries with significant regulatory capacity (USA, Australia, New Zealand). Thus, we will seek data sharing agreements so that results from experiments may be used within all three countries and treat regulatory requirements as a minimum. Species-specific, scalable, and socially acceptable new eradication tools could produce substantial biodiversity benefits not possible with current technologies. Gene drive innovation may provide such a tool for invasive species management and be potentially transformative and worthy of exploring in an inclusive, responsible, and ethical manner.

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This plan has been developed to reflect the essential steps to initiate, conduct and terminate an emergency marine spill response in Niue NATPLAN provides a concise and easy to follow guide to the management of spill response and associated linkages to supporting documentation. This plan consists of two main parts, Part A: The core plan text designed to provide key supporting information to assist with spill response operations and planning. Part B: Appendixes which contain Operational information for Oil Spill Planning, Preparedness & Response.

This plan has been developed to reflect the essential steps to initiate, conduct and terminate an emergency marine spill response in Samoa NATPLAN provides a concise and easy to follow guide to the management of spill response and associated linkages to supporting documentation. This plan consists of two main parts, Part A: The core plan text designed to provide key supporting information to assist with spill response operations and planning. Part B: Appendixes which contain Operational information for Oil Spill Planning, Preparedness & Response.

This plan has been developed to reflect the essential steps to initiate, conduct and terminate an emergency marine spill response in Solomon Islands NATPLAN provides a concise and easy to follow guide to the management of spill response and associated linkages to supporting documentation. This plan consists of two main parts, Part A: The core plan text designed to provide key supporting information to assist with spill response operations and planning. Part B: Appendixes which contain Operational information for Oil Spill Planning, Preparedness & Response.